Emerging Mechanisms of Innate Immunity and Their Translational Potential in Inflammatory Bowel Disease

Activation of the innate immune system through pattern-recognition receptor (PRR) signaling plays a pivotal role in the early induction of host defense following exposure to pathogens. Loss of intestinal innate immune regulation leading aberrant immune responses has been implicated in the pathogenes...

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Bibliographic Details
Main Authors: Daniele Corridoni, Thomas Chapman, Tim Ambrose, Alison Simmons
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Medicine
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmed.2018.00032/full