Musashi-1 promotes cancer stem cell properties of glioblastoma cells via upregulation of YTHDF1

Abstract Background Glioblastoma (GBM) is the most lethal brain tumor characterized by high morbidity and limited treatment options. Tumor malignancy is usually associated with the epigenetic marks, which coordinate gene expression to ascertain relevant phenotypes. One of such marks is m6A modificat...

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Bibliographic Details
Main Authors: Aliaksandr A. Yarmishyn, Yi-Ping Yang, Kai-Hsi Lu, Yi-Chen Chen, Yueh Chien, Shih-Jie Chou, Ping-Hsing Tsai, Hsin-I. Ma, Chian-Shiu Chien, Ming-Teh Chen, Mong-Lien Wang
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-020-01696-9