Trans-10,cis-12 CLA increases adipocyte lipolysis and alters lipid droplet-associated proteins: role of mTOR and ERK signaling

Trans-10,cis-12 CLA increases adipocyte lipolysis and alters lipid droplet-associated proteins: role of mTOR and ERK signaling

Lipiddroplet-associated proteins play an important role in adipocyte triglyceride (TG) metabolism. Here, weshow that trans-10,cis-12 conjugated linoleic acid (CLA), but notcis-9,trans-11 CLA, increased lipolysis and altered human adipocyte lipid dropletmorphology. Before this change in morphology, t...

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Bibliographic Details
Main Authors: Soonkyu Chung, Jonathan Mark Brown, MariaBoysen Sandberg, Michael McIntosh
Format: Article
Language:English
Published: Elsevier 2005-05-01
Series:Journal of Lipid Research
Subjects:
conjugated linoleicacid
perilipin
adipose differentiation-relatedprotein
triglycerides
mammalian target ofrapamycin
mitogen-activated protein kinase kinase/extracellular signal-related kinasesignaling
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520339717

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http://www.sciencedirect.com/science/article/pii/S0022227520339717

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