PARP activity and inhibition in fetal and adult oligodendrocyte precursor cells: Effect on cell survival and differentiation
Poly (ADP-ribose) polymerase (PARP) family members are ubiquitously expressed and play a key role in cellular processes, including DNA repair and cell death/survival balance. Accordingly, PARP inhibition is an emerging pharmacological strategy for cancer and neurodegenerative diseases. Consistent ev...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-07-01
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Series: | Stem Cell Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506117300983 |