Fibroblast growth factor receptor 3 in hepatocytes protects from toxin-induced liver injury and fibrosis

Fibroblast growth factor receptor 3 in hepatocytes protects from toxin-induced liver injury and fibrosis

Summary: The liver's remarkable regenerative capacity is orchestrated by several growth factors and cytokines. Fibroblast growth factor receptor 3 (Fgfr3) is frequently overexpressed in hepatocellular carcinoma and promotes cancer aggressiveness, whereas its role in liver homeostasis, repair an...

Full description

Bibliographic Details
Main Authors: Abbie E. Fearon, Coenraad F. Slabber, Andrii Kuklin, Marc Bachofner, Luigi Tortola, Lea Pohlmeier, Sophia Pantasis, Thorsten Hornemann, Lin Chen, Manfred Kopf, Sabine Werner
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:iScience
Subjects:
Biological sciences
cell biology
molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221011111

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221011111

Similar Items