Par-complex aPKC and Par3 cross-talk with innate immunity NF-κB pathway in epithelial cells
Summary Components of the Par-complex, atypical PKC and Par3, have been found to be downregulated upon activation of NF-κB in intestinal epithelial cells. To determine their possible role in pro-inflammatory responses we transduced Caco-2 human colon carcinoma cells with constitutively active (ca) P...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2013-10-01
|
Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/2/11/1264 |