Par-complex aPKC and Par3 cross-talk with innate immunity NF-κB pathway in epithelial cells

Summary Components of the Par-complex, atypical PKC and Par3, have been found to be downregulated upon activation of NF-κB in intestinal epithelial cells. To determine their possible role in pro-inflammatory responses we transduced Caco-2 human colon carcinoma cells with constitutively active (ca) P...

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Bibliographic Details
Main Authors: Radia Forteza, Flavia A. Wald, Anastasia Mashukova, Zhanna Kozhekbaeva, Pedro J. Salas
Format: Article
Language:English
Published: The Company of Biologists 2013-10-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/11/1264