CD4+CD25hiCD127low regulatory T cells are increased in oral squamous cell carcinoma patients.

CD4+CD25hiCD127low regulatory T cells are increased in oral squamous cell carcinoma patients.

Regulatory T cells (Tregs), a subset of CD4+ T cells plays a pivotal role in regulating the immune system. An increase in Treg numbers enables cancer progression by dampening the immune system and allowing tumor cells to evade immune detection and destruction. An increase in Treg numbers and express...

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Bibliographic Details
Main Authors: Kue Peng Lim, Nicole Ai Leng Chun, Siti Mazlipah Ismail, Mannil Thomas Abraham, Mohd Nury Yusoff, Rosnah Binti Zain, Wei Cheong Ngeow, Sathibalan Ponniah, Sok Ching Cheong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4143252?pdf=render

Internet

http://europepmc.org/articles/PMC4143252?pdf=render

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