B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies.

B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies.

Human cytomegalovirus (HCMV), a herpesvirus, is a ubiquitously distributed pathogen that causes severe disease in immunosuppressed patients and infected newborns. Efforts are underway to prepare effective subunit vaccines and therapies including antiviral antibodies. However, current vaccine efforts...

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Bibliographic Details
Main Authors: Sonja Pötzsch, Nadja Spindler, Anna-Katharina Wiegers, Tanja Fisch, Pia Rücker, Heinrich Sticht, Nina Grieb, Tina Baroti, Florian Weisel, Thomas Stamminger, Luis Martin-Parras, Michael Mach, Thomas H Winkler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3154849?pdf=render

Internet

http://europepmc.org/articles/PMC3154849?pdf=render

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