Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap.

Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap.

Recent studies suggest that some monoclonal antibodies (mAbs) specific for ebolavirus glycoprotein (GP) can protect experimental animals against infections. Most mAbs isolated from ebolavirus survivors appeared to target the glycan cap or the stalk region of the viral GP, which is the envelope prote...

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Bibliographic Details
Main Authors: Philipp A Ilinykh, Rodrigo I Santos, Bronwyn M Gunn, Natalia A Kuzmina, Xiaoli Shen, Kai Huang, Pavlo Gilchuk, Andrew I Flyak, Patrick Younan, Galit Alter, James E Crowe, Alexander Bukreyev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6107261?pdf=render

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http://europepmc.org/articles/PMC6107261?pdf=render

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