Priapism in sickle cell disease: Associations between NOS3 and EDN1 genetic polymorphisms and laboratory biomarkers.

Priapism is a urologic emergency characterized by an uncontrolled, persistent and painful erection in the absence of sexual stimulation, which can lead to penile fibrosis and impotence. It is highly frequent in sickle cell disease (SCD) associated with hemolytic episodes. Our aim was to investigate...

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Main Authors: Camylla Vilas Boas Figueiredo, Rayra Pereira Santiago, Caroline Conceição da Guarda, Rodrigo Mota Oliveira, Luciana Magalhães Fiuza, Sètondji Cocou Modeste Alexandre Yahouédéhou, Suéllen Pinheiro Carvalho, Joelma Santana Dos Santos Neres, Antonio Mateus de Jesus Oliveira, Cleverson Alves Fonseca, Valma Maria Lopes Nascimento, Isa Menezes Lyra, Milena Magalhães Aleluia, Marilda Souza Goncalves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0246067