Novel inhibitor design for hemagglutinin against H1N1 influenza virus by core hopping method.

The worldwide spread of H1N1 avian influenza and the increasing reports about its resistance to the current drugs have made a high priority for developing new anti-influenza drugs. Owing to its unique function in assisting viruses to bind the cellular surface, a key step for them to subsequently pen...

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Bibliographic Details
Main Authors: Xiao-Bo Li, Shu-Qing Wang, Wei-Ren Xu, Run-Ling Wang, Kuo-Chen Chou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3227604?pdf=render