Intracellular and Extracellular Lipopolysaccharide Signaling in Sepsis: Avenues for Novel Therapeutic Strategies

Sepsis is defined as organ dysfunction due to a dysregulated systemic host response to infection. During gram-negative bacterial infection and other acute illness such as absorption from the gut infection, lipopolysaccharide (LPS) is a major mediator in sepsis. LPS is able to trigger inflammation th...

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Bibliographic Details
Main Authors: Ramy S. Gabarin, Manshu Li, Paige A. Zimmel, John C. Marshall, Yimin Li, Haibo Zhang
Format: Article
Language:English
Published: Karger Publishers 2021-05-01
Series:Journal of Innate Immunity
Subjects:
Online Access:https://www.karger.com/Article/FullText/515740