Age and Influenza-Specific Pre-Vaccination Antibodies Strongly Affect Influenza Vaccine Responses in the Icelandic Population whereas Disease and Medication Have Small Effects

Age and Influenza-Specific Pre-Vaccination Antibodies Strongly Affect Influenza Vaccine Responses in the Icelandic Population whereas Disease and Medication Have Small Effects

Influenza vaccination remains the best strategy for the prevention of influenza virus-related disease and reduction of disease severity and mortality. However, there is large individual variation in influenza vaccine responses. In this study, we investigated the effects of gender, age, underlying di...

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Bibliographic Details
Main Authors: Thorunn A. Olafsdottir, Kristjan F. Alexandersson, Gardar Sveinbjornsson, Giulia Lapini, Laura Palladino, Emanuele Montomoli, Giuseppe Del Giudice, Daniel F. Gudbjartsson, Ingileif Jonsdottir
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
influenza vaccine
pre-vaccination antibody titer
age effect
underlying diseases
medication
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01872/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01872/full

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