Multiple aspects of gene dysregulation in Huntington’s Disease.

Huntington’s Disease (HD) is a genetic neurodegenerative disease caused by a CAG expansion in the gene encoding Huntingtin (Htt). It is characterized by chorea, cognitive and psychiatric disorders. The most affected brain region is the striatum, and the clinical symptoms are directly correlated to t...

Full description

Bibliographic Details
Main Authors: Lara eMoumne, Sandrine eBetuing, Jocelyne eCaboche
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00127/full