Interaction of Tau with Fe65 links tau to APP

Interaction of Tau with Fe65 links tau to APP

The β-amyloid precursor protein APP and the microtubule-associated protein Tau play a crucial role in the pathogenesis of Alzheimer's disease (AD). However, the possible molecular events linking these two proteins are still unknown. Here, we show that Fe65, one of the ligands of the APP cytodom...

Full description

Bibliographic Details
Main Authors: Christian Barbato, Nadia Canu, Nicola Zambrano, Annalucia Serafino, Giuseppina Minopoli, Maria Teresa Ciotti, Giuseppina Amadoro, Tommaso Russo, Pietro Calissano
Format: Article
Language:English
Published: Elsevier 2005-03-01
Series:Neurobiology of Disease
Subjects:
Tau
Fe65
Tau phosphorylation
APP
Alzheimer's disease
Cerebellar granule neurons
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104002438

Internet

http://www.sciencedirect.com/science/article/pii/S0969996104002438

Similar Items