Gene expression profiling of human alveolar macrophages infected by <it>B. anthracis </it>spores demonstrates TNF-α and NF-κb are key components of the innate immune response to the pathogen

Gene expression profiling of human alveolar macrophages infected by <it>B. anthracis </it>spores demonstrates TNF-α and NF-κb are key components of the innate immune response to the pathogen

<p>Abstract</p> <p>Background</p> <p><it>Bacillus anthracis</it>, the etiologic agent of anthrax, has recently been used as an agent of bioterrorism. The innate immune system initially appears to contain the pathogen at the site of entry. Because the human a...

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Bibliographic Details
Main Authors: Hurst Robert E, Booth J Leland, Chakrabarty Kaushik, Wu Wenxin, Dozmorov Mikhail, Coggeshall K Mark, Metcalf Jordan P
Format: Article
Language:English
Published: BMC 2009-09-01
Series:BMC Infectious Diseases
Online Access:http://www.biomedcentral.com/1471-2334/9/152

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http://www.biomedcentral.com/1471-2334/9/152

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