Temporal change in Syndecan-1 as a therapeutic target and a biomarker for the severity classification of COVID-19

Temporal change in Syndecan-1 as a therapeutic target and a biomarker for the severity classification of COVID-19

Abstract Background Coronavirus disease 2019 (COVID-19) pneumonitis associated with severe respiratory failure is associated with high mortality. The pathogenesis of COVID-19 is associated with microembolism or microvascular endothelial injuries. Here, we report that syndecan-1 (SDC-1), a component...

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Bibliographic Details
Main Authors: Fumihiro Ogawa, Yasufumi Oi, Kento Nakajima, Reo Matsumura, Tomoki Nakagawa, Takao Miyagawa, Kazuya Sakai, Ryo Saji, Hayato Taniguchi, Kohei Takahashi, Takeru Abe, Masayuki Iwashita, Mototsugu Nishii, Ichiro Takeuchi
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Thrombosis Journal
Subjects:
COVID-19
Syndecan-1
Endothelial injury
Glycocalyx
Severity
Classification
Online Access:https://doi.org/10.1186/s12959-021-00308-4

Internet

https://doi.org/10.1186/s12959-021-00308-4

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