Histone Sample Preparation for Bottom-Up Mass Spectrometry: A Roadmap to Informed Decisions

Histone Sample Preparation for Bottom-Up Mass Spectrometry: A Roadmap to Informed Decisions

Histone-based chromatin organization enabled eukaryotic genome complexity. This epigenetic control mechanism allowed for the differentiation of stable gene-expression and thus the very existence of multicellular organisms. This existential role in biology makes histones one of the most complexly mod...

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Bibliographic Details
Main Authors: Simon Daled, Sander Willems, Bart Van Puyvelde, Laura Corveleyn, Sigrid Verhelst, Laura De Clerck, Dieter Deforce, Maarten Dhaenens
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Proteomes
Subjects:
histone code
coverage
epigenetics
mass spectrometry
sample preparation
workflow optimization
Online Access:https://www.mdpi.com/2227-7382/9/2/17

Internet

https://www.mdpi.com/2227-7382/9/2/17

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