Histone Sample Preparation for Bottom-Up Mass Spectrometry: A Roadmap to Informed Decisions
Histone-based chromatin organization enabled eukaryotic genome complexity. This epigenetic control mechanism allowed for the differentiation of stable gene-expression and thus the very existence of multicellular organisms. This existential role in biology makes histones one of the most complexly mod...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-04-01
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Series: | Proteomes |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-7382/9/2/17 |