Differential regulation and recovery of intracellular Ca2+ in cerebral and small mesenteric arterial smooth muscle cells of simulated microgravity rat.

BACKGROUND: The differential adaptations of cerebrovasculature and small mesenteric arteries could be one of critical factors in postspaceflight orthostatic intolerance, but the cellular mechanisms remain unknown. We hypothesize that there is a differential regulation of intracellular Ca(2+) determi...

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Main Authors: Jun-Hui Xue, Lian-Hong Chen, Hua-Zhou Zhao, Yong-Dong Pu, Han-Zhong Feng, Yu-Guang Ma, Jin Ma, Yao-Ming Chang, Zuo-Ming Zhang, Man-Jiang Xie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3097196?pdf=render