Uncovering deeply conserved motif combinations in rapidly evolving noncoding sequences

Uncovering deeply conserved motif combinations in rapidly evolving noncoding sequences

Abstract Background Animal genomes contain thousands of long noncoding RNA (lncRNA) genes, a growing subset of which are thought to be functionally important. This functionality is often mediated by short sequence elements scattered throughout the RNA sequence that correspond to binding sites for sm...

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Bibliographic Details
Main Authors: Caroline Jane Ross, Aviv Rom, Amit Spinrad, Dikla Gelbard-Solodkin, Neta Degani, Igor Ulitsky
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Genome Biology
Subjects:
Long noncoding RNA
Molecular evolution
Homology
Integer linear programming
OIP5-AS1
CHD2
Online Access:https://doi.org/10.1186/s13059-020-02247-1

Internet

https://doi.org/10.1186/s13059-020-02247-1

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