The identification and structure of an N-terminal PR domain show that FOG1 is a member of the PRDM family of proteins.

The identification and structure of an N-terminal PR domain show that FOG1 is a member of the PRDM family of proteins.

FOG1 is a transcriptional regulator that acts in concert with the hematopoietic master regulator GATA1 to coordinate the differentiation of platelets and erythrocytes. Despite considerable effort, however, the mechanisms through which FOG1 regulates gene expression are only partially understood. Her...

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Bibliographic Details
Main Authors: Molly K Clifton, Belinda J Westman, Sock Yue Thong, Mitchell R O'Connell, Michael W Webster, Nicholas E Shepherd, Kate G Quinlan, Merlin Crossley, Gerd A Blobel, Joel P Mackay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25162672/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25162672/?tool=EBI

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