Vaccination Drives Changes in Metabolic and Virulence Profiles of Streptococcus pneumoniae.

The bacterial pathogen, Streptococcus pneumoniae (the pneumococcus), is a leading cause of life-threatening illness and death worldwide. Available conjugate vaccines target only a small subset (up to 13) of >90 known capsular serotypes of S. pneumoniae and, since their introduction, increases in...

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Bibliographic Details
Main Authors: Eleanor R Watkins, Bridget S Penman, José Lourenço, Caroline O Buckee, Martin C J Maiden, Sunetra Gupta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005034