Tick-Borne Flaviviruses Depress AKT Activity during Acute Infection by Modulating AKT1/2

Tick-borne flaviviruses (TBFVs) are reemerging public health threats. To develop therapeutics against these pathogens, increased understanding of their interactions with the mammalian host is required. The PI3K-AKT pathway has been implicated in TBFV persistence, but its role during acute virus infe...

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Bibliographic Details
Main Authors: Joshua M. Kirsch, Luwanika Mlera, Danielle K. Offerdahl, Marthe VanSickle, Marshall E. Bloom
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Viruses
Subjects:
AKT
Online Access:https://www.mdpi.com/1999-4915/12/10/1059