Identification of the Actinomycin D Biosynthetic Pathway from Marine-Derived <i>Streptomyces costaricanus</i> SCSIO ZS0073

Bioactive secondary metabolites from <i>Streptomycetes</i> are important sources of lead compounds in current drug development. <i>Streptomyces costaricanus</i> SCSIO ZS0073, a mangrove-derived actinomycete, produces actinomycin D, a clinically used therapeutic for Wilm&#...

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Bibliographic Details
Main Authors: Mengchan Liu, Yanxi Jia, Yunchang Xie, Chunyan Zhang, Junying Ma, Changli Sun, Jianhua Ju
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/17/4/240