5-(Carbamoylmethylene)-oxazolidin-2-ones as a Promising Class of Heterocycles Inducing Apoptosis Triggered by Increased ROS Levels and Mitochondrial Dysfunction in Breast and Cervical Cancer

5-(Carbamoylmethylene)-oxazolidin-2-ones as a Promising Class of Heterocycles Inducing Apoptosis Triggered by Increased ROS Levels and Mitochondrial Dysfunction in Breast and Cervical Cancer

Oxazolidinones are antibiotics that inhibit protein synthesis by binding the 50S ribosomal subunit. Recently, numerous worldwide researches focused on their properties and possible involvement in cancer therapy have been conducted. Here, we evaluated in vitro the antiproliferative activity of some 5...

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Bibliographic Details
Main Authors: Biagio Armentano, Rosita Curcio, Matteo Brindisi, Raffaella Mancuso, Vittoria Rago, Ida Ziccarelli, Luca Frattaruolo, Marco Fiorillo, Vincenza Dolce, Bartolo Gabriele, Anna Rita Cappello
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomedicines
Subjects:
oxazolidinones
apoptosis
mitochondria
ros
anticancer compounds
Online Access:https://www.mdpi.com/2227-9059/8/2/35

Internet

https://www.mdpi.com/2227-9059/8/2/35

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