Is there a renoprotective value to leukodepletion during heart valve surgery? A randomized controlled trial (ROLO)

Is there a renoprotective value to leukodepletion during heart valve surgery? A randomized controlled trial (ROLO)

Abstract Background Acute Kidney Injury (AKI) adversely affects outcomes after cardiac surgery. A major mediator of AKI is the activation of leukocytes through exposure to the cardiopulmonary bypass circuit. We evaluate the use of leukodepletion filters throughout bypass to protect against post-oper...

Full description

Bibliographic Details
Main Authors: Espeed Khoshbin, Sally Spencer, Laurence Solomon, Augustine Tang, Stephen Clark, Elizabeth Stokes, Sarah Wordsworth, Lucy Dabner, Julia Edwards, Barnaby Reeves, Chris Rogers
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Cardiac surgery
Heart valve
Cardiopulmonary bypass
Acute kidney injury
Leukodepletion
Online Access:https://doi.org/10.1186/s13019-021-01402-4

Internet

https://doi.org/10.1186/s13019-021-01402-4

Similar Items