Characterization of DNA binding property of the HIV-1 host factor and tumor suppressor protein Integrase Interactor 1 (INI1/hSNF5).

Characterization of DNA binding property of the HIV-1 host factor and tumor suppressor protein Integrase Interactor 1 (INI1/hSNF5).

Integrase Interactor 1 (INI1/hSNF5) is a component of the hSWI/SNF chromatin remodeling complex. The INI1 gene is either deleted or mutated in rhabdoid cancers like ATRT (Atypical terratoid and rhabdoid tumor). INI1 is also a host factor for HIV-1 replication. INI1 binds DNA non-specifically. Howeve...

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Bibliographic Details
Main Authors: Supratik Das, Baisakhi Banerjee, Maidul Hossain, Muruganandan Thangamuniyandi, Saumya Dasgupta, Nipa Chongdar, Gopinatha Suresh Kumar, Gautam Basu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3701577?pdf=render

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http://europepmc.org/articles/PMC3701577?pdf=render

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