Mutational analysis of two residues in the DYRK homology box of the protein kinase DYRK1A

Abstract Objective Dual specificity tyrosine phosphorylation-regulated kinases (DYRK) contain a characteristic sequence motif (DYRK homology box, DH box) that is located N-terminal of the catalytic domain and supports the autophosphorylation of a conserved tyrosine during maturation of the catalytic...

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Bibliographic Details
Main Authors: Esti Wahyu Widowati, Simone Bamberg-Lemper, Walter Becker
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Research Notes
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13104-018-3416-4