Regulation of P450-mediated permethrin resistance in Culex quinquefasciatus by the GPCR/Gαs/AC/cAMP/PKA signaling cascade

Regulation of P450-mediated permethrin resistance in Culex quinquefasciatus by the GPCR/Gαs/AC/cAMP/PKA signaling cascade

This study explores the role of G-protein-coupled receptor-intracellular signaling in the development of P450-mediated insecticide resistance in mosquitoes, Culex quinquefasciatus, focusing on the essential function of the GPCRs and their downstream effectors of Gs alpha subunit protein (Gαs) and ad...

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Bibliographic Details
Main Authors: Ting Li, Nannan Liu
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
GPCR regulatory pathway
G-protein
Adenylyl cyclase
Tissue-specific expression
Insecticide resistance
Mosquitoes
Online Access:http://www.sciencedirect.com/science/article/pii/S240558081730136X

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http://www.sciencedirect.com/science/article/pii/S240558081730136X

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