QSM is an imaging biomarker for chronic glial activation in multiple sclerosis lesions

QSM is an imaging biomarker for chronic glial activation in multiple sclerosis lesions

Abstract Background Inflammation in chronic active lesions occurs behind a closed blood–brain barrier and cannot be detected with MRI. Activated microglia are highly enriched for iron and can be visualized with quantitative susceptibility mapping (QSM), an MRI technique used to delineate iron. Objec...

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Bibliographic Details
Main Authors: Kelly M. Gillen, Mayyan Mubarak, Calvin Park, Gerald Ponath, Shun Zhang, Alexey Dimov, Maya Levine‐Ritterman, Steven Toro, Weiyuan Huang, Stephanie Amici, Ulrike W. Kaunzner, Susan A. Gauthier, Mireia Guerau‐de‐Arellano, Yi Wang, Thanh D. Nguyen, David Pitt
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.51338

Internet

https://doi.org/10.1002/acn3.51338

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