Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes.

Systemic lupus erythematosus (SLE) is a genetically complex disease with heterogeneous clinical manifestations. Recent studies have greatly expanded the number of established SLE risk alleles, but the distribution of multiple risk alleles in cases versus controls and their relationship to subphenoty...

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Bibliographic Details
Main Authors: Kimberly E Taylor, Sharon A Chung, Robert R Graham, Ward A Ortmann, Annette T Lee, Carl D Langefeld, Chaim O Jacob, M Ilyas Kamboh, Marta E Alarcón-Riquelme, Betty P Tsao, Kathy L Moser, Patrick M Gaffney, John B Harley, Michelle Petri, Susan Manzi, Peter K Gregersen, Timothy W Behrens, Lindsey A Criswell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3040652?pdf=render