<it>MDM2 </it>gene SNP309 T/G and <it>p53 </it>gene SNP72 G/C do not influence diffuse large B-cell non-Hodgkin lymphoma onset or survival in central European Caucasians

<it>MDM2 </it>gene SNP309 T/G and <it>p53 </it>gene SNP72 G/C do not influence diffuse large B-cell non-Hodgkin lymphoma onset or survival in central European Caucasians

<p>Abstract</p> <p>Background</p> <p>SNP309 T/G (rs2279744) causes higher levels of MDM2, the most important negative regulator of the p53 tumor suppressor. SNP72 G/C (rs1042522) gives rise to a p53 protein with a greatly reduced capacity to induce apoptosis. Both polym...

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Bibliographic Details
Main Authors: Landt Olfert, Truemper Lorenz, Kreuz Markus, Kerschenmeyer Lynn, Mueller Monika, Wabo Alain, Parisot Frédérique, Bittenbring Joerg, Menzel Alain, Pfreundschuh Michael, Roemer Klaus
Format: Article
Language:English
Published: BMC 2008-04-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/116

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http://www.biomedcentral.com/1471-2407/8/116

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