Tuberatolide B Suppresses Cancer Progression by Promoting ROS-Mediated Inhibition of STAT3 Signaling

Tuberatolide B Suppresses Cancer Progression by Promoting ROS-Mediated Inhibition of STAT3 Signaling

Tuberatolide B (TTB, C27H34O4) is a diastereomeric meroterpenoid isolated from the Korean marine algae Sargassum macrocarpum. However, the anticancer effects of TTB remain unknown. In this study, we demonstrate that TTB inhibits tumor growth in breast, lung, colon, prostate, and cervical cancer cell...

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Bibliographic Details
Main Authors: Youn Kyung Choi, Junseong Kim, Kang Min Lee, Yu-Jeong Choi, Bo-Ram Ye, Min-Sun Kim, Seong-Gyu Ko, Seung-Hong Lee, Do-Hyung Kang, Soo-Jin Heo
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Marine Drugs
Subjects:
tuberatolide B
cancer
STAT3
ROS
DNA damage
Online Access:http://www.mdpi.com/1660-3397/15/3/55

Internet

http://www.mdpi.com/1660-3397/15/3/55

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