Downregulation of Interleukin-13 Receptor α2 Inhibits Angiogenic Formation Mediated by Chitinase 3-Like 1 in Late Atherosclerotic Lesions of apoE−/− Mice

Downregulation of Interleukin-13 Receptor α2 Inhibits Angiogenic Formation Mediated by Chitinase 3-Like 1 in Late Atherosclerotic Lesions of apoE−/− Mice

Aim: Chitinase 3-like 1 (CHI3L1) has the potential to prompt proliferation and angiogenic formation. Interleukin-13 receptor α2 (IL-13Rα2) was regarded as a receptor of CHI3L1; however, it is unknown whether CHI3L1 adjusts the neovascularization in late atherosclerotic lesions of apoE−/− mice via IL...

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Bibliographic Details
Main Authors: Qi Xue, Lei Chen, Jianwu Yu, Kewang Sun, Lifang Ye, Jianlei Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Physiology
Subjects:
angiogenesis
CHI3L1
IL-13Ra2
proliferation
signaling/signaling pathways
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.690109/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.690109/full

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