Can linear regression modeling help clinicians in the interpretation of genotypic resistance data? An application to derive a lopinavir-score.

Can linear regression modeling help clinicians in the interpretation of genotypic resistance data? An application to derive a lopinavir-score.

The question of whether a score for a specific antiretroviral (e.g. lopinavir/r in this analysis) that improves prediction of viral load response given by existing expert-based interpretation systems (IS) could be derived from analyzing the correlation between genotypic data and virological response...

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Main Authors: Alessandro Cozzi-Lepri, Mattia C F Prosperi, Jesper Kjær, David Dunn, Roger Paredes, Caroline A Sabin, Jens D Lundgren, Andrew N Phillips, Deenan Pillay, EuroSIDA Study, United Kingdom CHIC/United Kingdom HDRD Study
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3217925?pdf=render

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http://europepmc.org/articles/PMC3217925?pdf=render

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