Synthesis of Platinum(II) Complexes with Some 1-Methylnitropyrazoles and In Vitro Research on Their Cytotoxic Activity

Synthesis of Platinum(II) Complexes with Some 1-Methylnitropyrazoles and In Vitro Research on Their Cytotoxic Activity

A series of eight novel platinum(II) complexes were synthesized by the reaction of the appropriate 1-methylnitropyrazole derivatives with K<sub>2</sub>PtCl<sub>4</sub> and characterized by elemental analysis, ESI MS spectrometry, <sup>1</sup>H NMR, <sup>195&...

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Bibliographic Details
Main Authors: Henryk Mastalarz, Agnieszka Mastalarz, Joanna Wietrzyk, Magdalena Milczarek, Andrzej Kochel, Andrzej Regiec
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pharmaceuticals
Subjects:
nitropyrazoles-Pt(II)complexes
synthesis
structural analysis
LogP
cellular platinum uptake
antiproliferative activity
Online Access:https://www.mdpi.com/1424-8247/13/12/433

Internet

https://www.mdpi.com/1424-8247/13/12/433

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