Recombinant Lactaptin Induces Immunogenic Cell Death and Creates an Antitumor Vaccination Effect in Vivo with Enhancement by an IDO Inhibitor

Recombinant Lactaptin Induces Immunogenic Cell Death and Creates an Antitumor Vaccination Effect in Vivo with Enhancement by an IDO Inhibitor

Natural compounds of various origins are intensively investigated for their antitumor activity. Potential benefits of antitumor therapy can be achieved when cytotoxic agents kill cancer cells and these dying cancer cells drive adoptive immunity to the tumor. This strategy was successfully demonstrat...

Full description

Bibliographic Details
Main Authors: Olga Troitskaya, Mikhail Varlamov, Anna Nushtaeva, Vladimir Richter, Olga Koval
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
milk peptides
recombinant lactaptin
immunogenic cell death
antitumor vaccination
indoleamine 2,3-dioxygenase inhibitor
Online Access:https://www.mdpi.com/1420-3049/25/12/2804

Internet

https://www.mdpi.com/1420-3049/25/12/2804

Similar Items