A Single-Nucleotide Polymorphism of α<sub>V</sub>β<sub>3</sub> Integrin Is Associated with the Andes Virus Infection Susceptibility

The <i>Andes</i> <i>Orthohantavirus</i> (ANDV), which causes the hantavirus cardiopulmonary syndrome, enters cells via integrins, and a change from leucine to proline at residue 33 in the PSI domain (L33P), impairs ANDV recognition. We assessed the association between this hu...

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Bibliographic Details
Main Authors: Constanza Martínez-Valdebenito, Jenniffer Angulo, Nicole Le Corre, Claudia Marco, Cecilia Vial, Juan Francisco Miquel, Jaime Cerda, Gregory Mertz, Pablo Vial, Marcelo Lopez-Lastra, Marcela Ferrés
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Viruses
Subjects:
SNP
Online Access:https://www.mdpi.com/1999-4915/11/2/169