Targeting ANXA1 abrogates Treg-mediated immune suppression in triple-negative breast cancer

BackgroundRegulatory T (Treg) cells play a negative role in anti-tumor immunity against triple-negative breast cancer, so it is of great significance to find the potential therapeutic target of Treg cells.MethodsFirst, Annexin A1 (ANXA1) expression and survival of patients with breast cancer were an...

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Bibliographic Details
Main Authors: Fang Bai, Yipeng Fu, Hongliang Chen, Mingdi Zhang, Qianru Huang, Kejin Wu
Format: Article
Language:English
Published: BMJ Publishing Group 2020-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/1/e000169.full