HIV-1 infection causes a down-regulation of genes involved in ribosome biogenesis.

HIV-1 infection causes a down-regulation of genes involved in ribosome biogenesis.

HIV-1 preferentially infects CD4+ T cells, causing fundamental changes that eventually lead to the release of new viral particles and cell death. To investigate in detail alterations in the transcriptome of the CD4+ T cells upon viral infection, we sequenced polyadenylated RNA isolated from Jurkat c...

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Bibliographic Details
Main Authors: Claudia L Kleinman, Margherita Doria, Elisa Orecchini, Erica Giuliani, Silvia Galardi, Nicolas De Jay, Alessandro Michienzi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0113908

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https://doi.org/10.1371/journal.pone.0113908

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