Small RNA Species and microRNA Profiles are Altered in Severe Asthma Nanovesicles from Broncho Alveolar Lavage and Associate with Impaired Lung Function and Inflammation

Small RNA Species and microRNA Profiles are Altered in Severe Asthma Nanovesicles from Broncho Alveolar Lavage and Associate with Impaired Lung Function and Inflammation

MicroRNAs are known to regulate important pathways in asthma pathology including the IL-6 and IFN pathways. MicroRNAs have been found not only within cells but also within extracellular vesicles such as exosomes. In this study, we particularly focused on microRNA cargo of nanovesicles in bronchoalve...

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Bibliographic Details
Main Authors: Ana S. Francisco-Garcia, Eva M. Garrido-Martín, Hitasha Rupani, Laurie C. K. Lau, Rocio T. Martinez-Nunez, Peter H. Howarth, Tilman Sanchez-Elsner
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Non-Coding RNA
Subjects:
micrornas
severe asthma
exosomes
lung function
fev<sub>1</sub>
eosinophils
neutrophils
Online Access:https://www.mdpi.com/2311-553X/5/4/51

Internet

https://www.mdpi.com/2311-553X/5/4/51

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