Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo.

The fungal pathogen Candida albicans is frequently associated with catheter-based infections because of its ability to form resilient biofilms. Prior studies have shown that the transcription factor Bcr1 governs biofilm formation in an in vitro catheter model. However, the mechanistic role of the Bc...

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Bibliographic Details
Main Authors: Clarissa J Nobile, David R Andes, Jeniel E Nett, Frank J Smith, Fu Yue, Quynh-Trang Phan, John E Edwards, Scott G Filler, Aaron P Mitchell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1487173?pdf=render