Comparative analysis of human γD-crystallin aggregation under physiological and low pH conditions.

Cataract, a major cause of visual impairment worldwide, is the opacification of the eye's crystalline lens due to aggregation of the crystallin proteins. The research reported here is aimed at investigating the aggregating behavior of γ-crystallin proteins in various incubation conditions. Thio...

Full description

Bibliographic Details
Main Authors: Josephine W Wu, Mei-Er Chen, Wen-Sing Wen, Wei-An Chen, Chien-Ting Li, Chih-Kai Chang, Chun-Hsien Lo, Hwai-Shen Liu, Steven S-S Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4229192?pdf=render