Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.

Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.

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Genome-wide association studies (GWAS) have defined over 150 genomic regions unequivocally containing variation predisposing to immune-mediated disease. Inferring disease biology from these observations, however, hinges on our ability to discover the molecular processes being perturbed by these risk...

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Bibliographic Details
Main Authors: Elizabeth J Rossin, Kasper Lage, Soumya Raychaudhuri, Ramnik J Xavier, Diana Tatar, Yair Benita, International Inflammatory Bowel Disease Genetics Constortium, Chris Cotsapas, Mark J Daly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3020935?pdf=render

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http://europepmc.org/articles/PMC3020935?pdf=render

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