An Underestimated Factor: The Extent of Cross-Reactions Modifying APIs in Surface-Modified Liposomal Preparations Caused by Comprised Activated Lipids

An Underestimated Factor: The Extent of Cross-Reactions Modifying APIs in Surface-Modified Liposomal Preparations Caused by Comprised Activated Lipids

Despite the nowadays available plentitude of strategies to selectively introduce functional surface modification of liposomes, in preclinical research this process is still primarily performed after liposomal preparation utilizing comprised activated phospholipids with functionalized head groups. Ho...

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Bibliographic Details
Main Authors: Max Sauter, Jürgen Burhenne, Walter E. Haefeli, Philipp Uhl
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
liposomes
surface modification
API-modification
head group-functionalized phospholipids
macromolecular drugs
cross-reaction
Online Access:https://www.mdpi.com/1420-3049/25/19/4436

Internet

https://www.mdpi.com/1420-3049/25/19/4436

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