Identification of Rev-erbα as a physiological repressor of apoC-III gene transcription1

Elevated serum levels of triglyceride-rich remnant lipoproteins (TRL) are a major risk factor predisposing a subject to atherosclerosis. Apolipoprotein C-III (apoC-III) is a major constituent of TRL that impedes triglyceride hydrolysis and remnant clearance and, as such, may exert pro-atherogenic ac...

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Bibliographic Details
Main Authors: Eric Raspé, Hélène Duez, Anethe Mansén, Coralie Fontaine, Catherine Fiévet, Jean-Charles Fruchart, Bjorn Vennström, Bart Staels
Format: Article
Language:English
Published: Elsevier 2002-12-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520327462