Chromatin Modifications and the DNA Damage Response to Ionizing Radiation

Chromatin Modifications and the DNA Damage Response to Ionizing Radiation

In order to survive, cells have evolved highly effective repair mechanisms to deal with the potentially lethal DNA damage produced by exposure to endogenous as well as exogenous agents. Ionizing radiation exposure induces highly lethal DNA damage, especially DNA double strand breaks (DSBs), that is...

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Bibliographic Details
Main Authors: Tej K Pandita, Rakesh eKumar, Nobuo eHorikoshi, Mayank eSingh, Arun eGupta, Hari S Misra, Kevin eAlbuquerque, Clayton R Hunt
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-01-01
Series:Frontiers in Oncology
Subjects:
DNA Repair
histone modification
DDR
HR
NHJE
DSB.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00214/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00214/full

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