Crystal structure of the complex mAb 17.2 and the C-terminal region of Trypanosoma cruzi P2β protein: implications in cross-reactivity.

Crystal structure of the complex mAb 17.2 and the C-terminal region of Trypanosoma cruzi P2β protein: implications in cross-reactivity.

Patients with Chronic Chagas' Heart Disease possess high levels of antibodies against the carboxyl-terminal end of the ribosomal P2ß protein of Trypanosoma cruzi (TcP2ß). These antibodies, as well as the murine monoclonal antibody (mAb) 17.2, recognize the last 13 amino acids of TcP2ß (called t...

Full description

Bibliographic Details
Main Authors: Juan Carlos Pizarro, Ginette Boulot, Graham A Bentley, Karina A Gómez, Johan Hoebeke, Mireille Hontebeyrie, Mariano J Levin, Cristian R Smulski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3206007?pdf=render

Internet

http://europepmc.org/articles/PMC3206007?pdf=render

Similar Items