Vildagliptin ameliorates pulmonary fibrosis in lipopolysaccharide-induced lung injury by inhibiting endothelial-to-mesenchymal transition

Abstract Background Pulmonary fibrosis is a late manifestation of acute respiratory distress syndrome (ARDS). Sepsis is a major cause of ARDS, and its pathogenesis includes endotoxin-induced vascular injury. Recently, endothelial-to-mesenchymal transition (EndMT) was shown to play an important role...

Full description

Bibliographic Details
Main Authors:	Toshio Suzuki, Yuji Tada, Santhi Gladson, Rintaro Nishimura, Iwao Shimomura, Satoshi Karasawa, Koichiro Tatsumi, James West
Format:	Article
Language:	English
Published:	BMC 2017-10-01
Series:	Respiratory Research
Subjects:	Endothelial-to-mesenchymal transition Pulmonary fibrosis Dipeptidyl peptidase 4 Post ARDS pulmonary fibrosis
Online Access:	http://link.springer.com/article/10.1186/s12931-017-0660-4

Internet

http://link.springer.com/article/10.1186/s12931-017-0660-4

Vildagliptin ameliorates pulmonary fibrosis in lipopolysaccharide-induced lung injury by inhibiting endothelial-to-mesenchymal transition

Internet

Similar Items